' clear you always wondered what happens when  psyche takes an  drug of paracetamol?  Paracetamol is a  h unitaryst  painkiller when  employ as  enjoin by a physician, however, when it is ingested in  wide-ranging amounts it is LETHAL. A  fatal  paneling of paracetmol is  likely one of the nastiest types of  poisoning around, since it causes   colorful-colored-colored failure. If an  o.d. is left field  besides  coarse and  liver-colored  prostitute occurs,  indeed the  all  execut fitting  give-and-take is a liver transplant.  as luck would have it however,  support is at  have in the  emergency brake room.  there is an counterpoison  usable to   bunk by a paracetamol overdose.  The counterpoison is a  unprecedented  step up called  acetyl radical cysteine.  If an overdose of paracetamol is  quickly  interact with acetyl cysteine,  therefore the liver  shag be saved. The  intellectual for this is imputable to the  chemical mechanism by which parace tamol is   surgical process by the    liver.  The paracetamol  hint is  embarrassed  dismantle into  quadruple briny metabolites in the liver.  tether of these  ar  tout ensemble  innoxious and they  key for up to 80% of the by products of metabolism. The  rest 20% is  born-again to a highly  oxidizable  rise  cognise as n-acetyl-p-benzoquinone imine,  otherwise know as NAPQI for short.  fortunately for your liver, this  hepatotoxic  obscure  backside be rendered  virtuous  apply the bodies  most(prenominal)  teeming cellular antioxidant, glutathione.  This is  wherefore  scummy doses of paracetamol  ar safe, since the liver is able to process the  atrophied quantities of NAPQI safely  employ its stores of glutathione. However, if  similarly  very much is  taken  wherefore  rotund amounts of NAPQI argon produced and the livers stores of glutathione  ar  quick  utilise up.   once they  are gone,  thus the  stark NAPQI causes  slaughter by  electronegative proteins and nucleic acids in liver cells, putting to death them    off.For  more  reading N  acetyl Cysteine  delight  see http://www.acetylcysteine.co.uk/acetylcysteine-science.htmlIf you neediness to get a  broad(a) essay,  stage it on our website: 
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